Hemodynamic simulation is an important tool for revealing the pathological mechanisms of the initiation

development

and onset of vascular disease (e.g.

arterial aneurysm

atherosclerotic plaque

etc.)

as well as for disease diagnosis and vascular surgery evaluation.Therefore

this type of simulation has become a popular research hotspot in the diagnosis and prediction of vascular disease. Macro-scale and multi-scale simulation of blood flow dynamics areadopted for thisreview on the basis of the different feature scales of blood flow in hemodynamic simulation. State-of-the-art research methods and key technologies of blood flow dynamics simulation methods that target different feature scales of blood flow are discussed.Subsequently

existing research difficulties and problems are summarized.Finally

trends in the further development of blood flow dynamics simulation methodsare examined. With the rising number of patients with vascular disease

the multiscale simulation of blood flow dynamics combined with the image-based modeling of vascular and physiological blood flow data is expected tobecome ahot topic of future research. Such studies are of great significance to improvethe level of vascular disease treatment in China.