N-dimensional Multimodality Medical Images Registration Based on Mutual Information[J]. Journal of Image and Graphics, 2009, 14(10): 2061. DOI: 10.11834/jig.20091022.
the multimodality medical image registration has been all confined in registering two images and rarely involved N-dimensional images (three and more than three dimensions). Using the expanded N-dimensional mutual information measure (E-NMIM) to register multiple images inefficient
and cannot meet the clinical requirement.In addition mutual information(MI) values are not necessarily nonnegative. In this paper
we introduce a new N-dimensional mutual information measure (N-NMIM)
which can ensure MI values are nonnegative
bounded to range from 1 to 2. At the same time
the rate of the registration has moved up. Then this definition is tested and proved to be effective on registration of three lumbar vertebra images through simulation