Jiang Shaofeng, Wan Hongping, Chen Zhen, Yang Suhua. Automatic brain extraction from cerebral MRI volume using region of interest[J]. Journal of Image and Graphics, 2013, 18(12): 1644-1650. DOI: 10.11834/jig.20131213.
Automatic extraction of brain tissue from MRI volume is an important step in the preprocessing of brain analysis. To improve the extraction result
a region of interest based method for automatic brain extraction was proposed. The first step of the proposed method was obtaining the brain region of interest with the brain extraction tool (BET) algorithm. Then a modified hybrid level set model was defined to obtain the true brain boundary. The modified hybrid level set model used a nonlinear speed function which can eliminate the boundary leakage effectively. 18 MRI volumes from internet brain segmentation repository (IBSR) were used in our experiment. The results obtained from our method were very similar with the results using manual extraction and almost achieved the best results on IBSR data compared with other methods. Experiment shows the proposed method is effective and robust.